Mindr Responds to US POINTER Results: The Future of Brain Health Must Be Digital, Scalable, and Equitable

This week, the long-awaited results from the US POINTER Trial — the largest randomized controlled study of multidomain lifestyle interventions for brain health in the United States — were published in JAMA. And the message is clear:

Lifestyle medicine works.

The POINTER trial followed over 2,500 older adults at risk of cognitive decline but without a dementia diagnosis. Over two years, participants in the intervention group received structured support around physical activity, nutrition, cognitive stimulation, social engagement, and regular health coaching.

The results showed meaningful cognitive benefits, especially in executive functioning and attention, among those receiving the lifestyle intervention compared to a control group. This builds on years of global evidence (including the FINGER trial in Finland) that show cognitive health can be protected, not just passively hoped for.

At Mindr, we’re not just celebrating these results. We’re building on them.

We support individuals concerned about cognitive decline — often caregivers or those with a family history of Alzheimer’s — through a digital platform that delivers personalized, AI-supported lifestyle interventions grounded in evidence. We meet people where they are, with tools that are accessible, scalable, and designed for real-life complexity.

We believe that:

  • Every caregiver deserves access to cognitive support, even if they can’t attend in-person programs

  • Digital health tools, when designed with empathy and evidence, can close the equity gap

  • The next chapter of brain health must include rigorous digital translation of what POINTER has proven in-person

We are actively exploring partnerships to test this hypothesis further.
Can digitally delivered lifestyle medicine protect the brain as well as in-person coaching?

We believe it can — and we intend to prove it.

To our friends in research, caregiving, aging, and digital health: we invite you to join us in making this next chapter real.

Mindr: because cognitive health belongs to everyone.

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